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Editor-in-Chief         

EB Liu XiaodongX.D Liu

 

 

 

 

 Dr. Liu Xiaodong
China Pharmaceutical University, China



Archive

Volume 1 Issue 1

     051

Adriamycin’s Hepatotoxic Effect Associated With Local Renin Angiotensin System

Cancer patient’s number is going to scale up every year. Adriamycin (ADR) is one of the most effective anticancer drug against to solid tumors. Unfortunately, the drug has a undesired side effect on some tissue including heart, liver, kidney, pancreas. Although many studies found that ADR’s toxic effect relate to oxidative stress, the exact molecular mechanisms underlying of its side effect has not completely understood.
     004


Target Specific Cancer Treatment with Carbon Monoxide Releasing Molecules

Carbon monoxide (CO) is a colorless, odorless, and tasteless gas which has been defined as “silent killer” for a long time. CO has strong affinity for hemoglobin, and CO-hemoglobin (carboxyhemoglobin) complex inhibits oxygen delivery to tissues by red blood cells. Apart from this poisoner effect, the therapeutic potential of CO has been extensively evaluated in pathogenesis of many diseases.

Journal Highlights

  • Narcotics substances
  • Psycho pharmaceutical
  • Stimulants
  • Hallucinogens
  • Drug toxicity
  • Hepatoxic Agents
  • Nephrotoxic Agents
  • Neurotoxic Agents
  • Cardiotoxic agents
  • Drugs Attacking Hematopoietic System
  • Drugs damaging the respiratory system
  • Carcinogens
  • Mutagens
  • Teratogens
  • Drug Sensitization
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